Xi Xin

Asarum, a name in traditional Chinese medicine, refers to the dried roots and rhizomes of the Araliaceae plant Northern Asarum (Asarum heterotropoides Fr. Schmidt var. mandshurium (Maxim.) Kitag.), Seoul Asarum (Asarum sieboldii Miq. var. seoulense Nakai, or Asarum sieboldii Miq. The first two are commonly known as “Liaoning Asarum” and are mainly produced in Liaoning, Jilin, and Heilongjiang; Asarum sieboldii Miq. is mainly produced in Shaanxi.According to traditional medicine, it has a pungent taste and warm nature, enters the Heart, Lung, and Kidney meridians, and possesses the effects of relieving exterior syndromes and dispelling cold, expelling wind and alleviating pain, unblocking the orifices, and warming the lungs to transform fluid retention. It is primarily used to treat wind-cold colds, headaches, toothaches, nasal congestion with runny nose, nasal discharge, chronic sinusitis, rheumatic arthralgia, and phlegm-fluid retention accompanied by wheezing and cough.

Chinese Name : 细辛

Latin Name : Asari Radix et Rhizoma

Aliases : Shao Xin, Xiao Xin, Xi Cao, Xi Tiao, Green-Beard Ginger, Single-Leaf Grass, Golden Basin Grass, Ten-Thousand-Disease Grass, Reclining Dragon Dan, Bell Flower, Four-Liang Hemp

Authentic Producing Area : Liaoning Xi Xin is primarily produced in Liaoning, Jilin, and Heilongjiang; Hua Xi Xin is primarily produced in Shaanxi

Nature, Flavor & Meridian Tropism : Pungent in taste, warm in nature; enters the Heart, Lung, and Kidney meridians

Benefits & Efficacy

Benefits

Relieves exterior syndromes and dispels cold; expels wind and alleviates pain; unblocks the orifices; warms the lungs and transforms phlegm.

Indications

Asari is primarily used to treat wind-cold colds, headaches, toothaches, nasal congestion with runny nose, nasal discharge, chronic sinusitis, rheumatic arthralgia, and phlegm-fluid retention with wheezing and cough.

Usage and Dosage

1. Internal use: Decocted as a soup, 1–3 g; as a powder, 0.5–1 g per dose. 2. External use: As needed.

Precautions

Patients requiring treatment with Chinese herbal medicine should first consult a licensed Traditional Chinese Medicine (TCM) hospital to receive a prescription following a professional TCM differential diagnosis.

Chemical Constituents

This product contains essential oils, whose main components include methyl eugenol, Asarum ether, and safrole, among others. It also contains N-isobutyl dodecatrienamide, racemic norwuyakine, sitosterol, and stigmasterol.

Pharmacological Actions

This product has antipyretic, analgesic, anti-inflammatory, anti-allergic, sedative, cardiotonic, and immunosuppressive effects.

Relevant Discussions

1. *Shennong’s Classic of Materia Medica*: “It treats coughing and wheezing, headaches with throbbing in the brain, stiffness in all joints, rheumatic arthralgia, and necrotic muscle tissue. It improves eyesight and clears the nine orifices.”

2. *Supplementary Notes on Materia Medica*: “If Asarum is used alone as a powder, the dose must not exceed half a qian bi; a larger dose may cause suffocation and blockage of the breath, and those unable to breathe may die.”

Applications

Clinical Applications

1. For treating external invasion by wind-cold with severe pain in the head and body, it is often combined with wind-dispelling and pain-relieving herbs such as Qianghuo, Fangfeng, and Bai Zhi, as in the Nine-Ingredient Qianghuo Decoction (*This Matter Is Hard to Know*); it is also suitable for wind-cold colds presenting with nasal congestion and runny nose, and is commonly combined with herbs such as Bai Zhi and Cang’erzi.When combined with Ma Huang and Fu Zi, it can treat external invasion due to yang deficiency, characterized by aversion to cold, fever, absence of sweat, and a deep pulse, as in the Ma Huang Fu Zi Xi Xin Decoction (*Treatise on Cold Damage*).

2. To treat Shaoyin-type headaches with cold feet, counterflow of qi, and a deep, fine pulse, it is often combined with Du Huo and Chuan Xiong, as in the Du Huo Xi Xin Decoction (*Causes, Symptoms, Pulse, and Treatment*);For treating external invasion by wind-pathogen causing unilateral or bilateral headaches, it is often used in combination with Chuanxiong, Bai Zhi, and Qianghuo, as in the Chuanxiong Cha Tiao San (from *Taiping Huimin Heji Jufang*); for wind-cold headaches characterized by pain so severe it feels as if the head is about to split, with a pulse that is faint, string-like, and tight, it should be combined with Chuanxiong, Ma Huang, and Fu Zi, as in the Xixin San (from *Puji Fang*).

3. To treat wind-cold toothache, Xixin may be used alone or decocted with Bai Zhi and Bi Bo for gargling; for toothache caused by stomach fire, it should be combined with herbs that clear stomach fire and drain heat, such as raw gypsum, Huang Lian, and Sheng Ma; for toothache caused by dental caries, it may be combined with decocted bee hive—which kills parasites and relieves pain—for gargling.

4. For treating bi syndrome caused by wind, cold, and dampness, as well as cold pain in the lower back and knees, Xi Xin both dispels the internal cold pathogen in the Shao Yin Kidney Meridian to restore yang and resolve stagnation, and expels wind-dampness from the tendons and bones to relieve bi syndrome and alleviate pain. Therefore, it is often combined with Du Huo, Sang Jisheng, and Fang Feng, as in the Du Huo Jisheng Decoction (*Essential Prescriptions Worth a Thousand Gold for Emergency Use*, abbreviated as *Qian Jin Fang*).

5. For nasal congestion, runny nose, and headache associated with nasal disorders such as nasal sinusitis, it is an excellent remedy. It should be combined with Bai Zhi, Cang Er Zi, and Xin Yi—herbs that dispel wind-cold and open the nasal passages.

6. For external invasion by wind-cold with internal retention of fluid, presenting as chills, fever, absence of sweat, shortness of breath, and cough,and copious, thin, clear phlegm, it is often used in combination with Ephedra, Cinnamon Twig, and Dried Ginger, as in the Minor Blue Dragon Decoction (*Treatise on Cold Damage*); if the condition is purely due to cold phlegm and fluid retention affecting the lungs, presenting with cough, chest fullness, and reverse qi with severe wheezing, it may be combined with Poria, Dried Ginger, and Schisandra, as in the Poria-Glycyrrhiza-Schisandra-Ginger-Asarum Decoction (*Essentials of the Golden Cabinet*).

Related Compatibility

1. Asarum combined with Chuanxiong: Asarum excels at dispelling wind, dispersing cold, and relieving pain; Chuanxiong excels at promoting blood circulation, regulating qi, dispelling wind, and relieving pain. When used together, they not only promote blood circulation and remove blood stasis but also dispel wind and relieve pain. When wind is dispelled, the ying and wei qi harmonize; when blood flows smoothly, wind naturally subsides.This combination is effective for treating head and body pain caused by exogenous wind-cold, and is also commonly used to treat wind-cold-damp bi syndrome and joint pain.

2. Asarum combined with Aconite: Asarum dispels wind-cold externally, eliminates yin-cold internally, warms and unblocks kidney qi, and opens the orifices; Aconite supplements fire, assists yang, dispels cold, and relieves pain.When used together, these two herbs provide warming, unblocking, and dispersing effects. They act both on the exterior via the Bladder Meridian and on the interior via the Kidney Meridian, complementing each other to achieve the effects of tonifying fire, assisting yang, dispelling cold, relieving pain, and resolving phlegm and fluid retention. This combination is suitable for chest pain caused by yang deficiency and yin excess, as well as coughing and wheezing due to yang deficiency with phlegm and fluid retention.

3. Asarum combined with Poria: Asarum is pungent and warm, excelling at warming the lungs and transforming fluid retention; Poria is sweet, bland, and neutral, excelling at strengthening the spleen, promoting diuresis, and draining dampness. When used together, their efficacy in warming and transforming phlegm and fluid retention is even more pronounced. This combination is suitable for cough and wheezing caused by phlegm and fluid retention stagnating in the lungs, characterized by copious, thin, clear, and white phlegm.

4. Asarum combined with raw gypsum: Asarum is pungent and warm, excelling at dispelling cold and relieving pain;raw gypsum is pungent, sweet, and extremely cold, and excels at clearing stomach heat. When used together, these two herbs combine cold and heat properties; the raw gypsum moderates the warm and hot nature of Asarum to harness its analgesic effect. This approach clears heat without causing stagnation and disperses without promoting heat, effectively clearing and purging stomach fire and relieving pain. It is commonly used to treat toothaches caused by ascending stomach fire.

5. Xi Xin Combined with Raw Rehmannia: Xi Xin is pungent, dispersing, warm, and unblocking; it dispels cold and relieves pain but can easily injure yin and promote heat. Raw Rehmannia is sweet and cold in nature; it nourishes yin and clears heat. The interplay of cold and heat, and the balance of strength and gentleness, results in the ability to clear heat and relieve pain. This combination is suitable for treating conditions such as headaches and toothaches caused by wind-fire rising upward.

Medicinal Identification

Asarum and Ephedra: Both can induce sweating and resolve exterior syndromes, and are similarly used to treat wind-cold colds. The difference lies in the fact that Asarum is pungent and warm, moving rapidly through the channels to reach both the exterior and interior; it can disperse wind-cold from the Lung and Foot-Shaoyin Kidney meridians. Although its ability to induce sweating is not as strong as that of Ephedra, its ability to dispel cold is superior. It treats general wind-cold colds but is particularly effective for cases where cold has invaded the Shaoyin channel—manifesting as an external pathogen with yang deficiency, characterized by absence of sweat, aversion to cold, fever, and a deep pulse.With its pungent, dispersing, and warming properties, it excels at unblocking orifices, relieving pain, warming the lungs, and transforming phlegm-fluid, making it particularly effective for treating disorders of the head and facial orifices, rheumatic arthralgia, and symptoms such as phlegm-fluid retention, wheezing, and cough.Ephedra (Ma Huang), with its pungent-opening and bitter-draining properties, focuses on promoting the defensive qi, opening the skin pores, unblocking the orifices, inducing sweating, and resolving exterior syndromes. It primarily dispels wind-cold from the Lung and Bladder meridians and is a potent diaphoretic and exterior-resolving herb. Therefore, it is primarily used to treat severe cases of wind-cold common cold characterized by external wind-cold constriction, stagnation of lung qi, obstruction of the orifices, and a solid exterior syndrome without sweating;It also has the functions of promoting lung function to relieve asthma and promoting diuresis to reduce swelling. It can be used for asthma, cough, and shortness of breath caused by stagnation of lung qi, as well as wind-damp edema characterized by generalized swelling resulting from wind pathogens invading the exterior.

Related Medicines

Xinqin Granules, Ditong Rhinitis Drops, Yitongshu Injection, and Kuanxiong Aerosol.

Related Prescriptions

Ephedra-Aconite-Asarum Decoction (*Treatise on Cold Damage*), Nine-Ingredient Qianghuo Decoction (*This Matter Is Hard to Know*), Minor Blue Dragon Decoction (*Treatise on Cold Damage*), Poria-Licorice-Five-Flavor-Ginger-Asarum Decoction (*Essentials of the Golden Cabinet*), and Duhuo-Parasite Decoction (*Essential Prescriptions Worth a Thousand Pieces of Gold*).

Medicinal Diet Therapy

Xixin-Fuzi-Dog Meat Decoction:

(1) Indications: Tonifies the kidneys and assists yang; transforms turbidity and opens the orifices. Suitable for elderly patients with deafness due to kidney yang deficiency and phlegm-turbidity obscuring the orifices, presenting with symptoms such as hearing loss, progressively declining ability to understand speech, mental dullness, soreness in the lower back and coldness in the knees, clear and copious nocturnal urination, a flabby physique, a pale and swollen tongue with a white and turbid coating, and a slow and weak pulse.

(2) Ingredients: 150 g dog meat, 6 g Asarum, 9 g processed Aconite, 18 g prepared Rehmannia, 6 g each of star anise and fennel.

(3) Preparation: Wash the dog meat and cut it into chunks. Rinse Asarum, processed Aconite, prepared Rehmannia, star anise, and fennel separately with clean water. Heat oil in a wok, stir-fry the dog meat until fragrant, then transfer it along with the other ingredients to a clay pot. Add an appropriate amount of water, bring to a boil over high heat, then reduce to low heat and simmer for 2–3 hours. Season to taste before serving.

(4) Usage: Serve as a side dish with meals.

Processing & Preparation

Harvesting & Processing

Harvest during the fruit ripening period in summer or early autumn; remove all above-ground parts and soil, then air-dry in the shade.

Processing Methods

1. Asarum: Take the raw herb, remove impurities, rinse thoroughly with running water, moisten slightly, cut into sections, and air-dry.

2. Honey-Fried Asarum: Take refined honey, dilute it with an appropriate amount of boiling water, add the cleaned Asarum sections, mix well, let stand until thoroughly infused, and heat over low heat. Stir-fry until it no longer sticks to the hands, then remove and let cool. Use 25 kg of honey per 100 kg of Asarum sections.

Storage Methods

Store in a dry, airtight container. Keep in a cool, dry place away from moisture.

Crude Drug Identification

Properties of Crude Drugs

1. Northern Asarum: Often curled into a ball. The rhizome grows horizontally and is irregularly cylindrical in shape, with short branches; it is 1–10 cm long and 0.2–0.4 cm in diameter. The surface is grayish-brown and rough, with annular nodes; internodes are 0.2–0.3 cm long, and the tips of the branches have bowl-shaped stem scars.The roots are slender and long, densely clustered on the nodes, 10–20 cm long, and 0.1 cm in diameter; the surface is grayish-yellow, smooth or with longitudinal wrinkles; they have fibrous roots and fibrous root scars; the texture is brittle, breaking easily, with a flat cross-section that is yellowish-white or white. It has a pungent aroma and a spicy, numbing taste.

2. Seoul Asarum: The rhizome has a diameter of 0.1–0.5 cm, with internodes 0.1–1 cm long.

3. Hua Asarum: The rhizome is 5–20 cm long, with a diameter of 0.1–0.2 cm and internodes 0.2–1 cm long. It has a relatively weak aroma.

Properties of Processed Slices

Presented in irregular segments. The rhizome is irregularly round, with a grayish-brown outer skin; ring-shaped nodes are sometimes visible. The roots are slender, with a grayish-yellow surface that is smooth or has longitudinal wrinkles. The cross-section is yellowish-white or white. It has a pungent, aromatic odor and a spicy, numbing taste.

Botanical Information

Botanical Classification

Species of the genus Asarum in the family Aristolochiaceae, including Northern Asarum, Seoul Asarum, or Chinese Asarum.

Morphological Characteristics

1. Northern Asarum: A perennial herb. It often curls into a tuft; the rhizome is creeping, with numerous slender roots growing from the nodes; when rubbed, it emits a pungent, aromatic scent. The leaves are ovate-cordate or nearly reniform, 4–9 cm long and 5–13 cm wide, with an acute or obtuse apex and a cordate base; the upper surface has sparse hairs along the veins, while the lower surface is more densely hairy; the bud bracts are nearly circular.Flowers are purplish-brown, rarely purplish-green, and solitary in the leaf axils; during flowering, they bend at a right angle at the apex, but stand erect when fruiting; the perianth tube is urn-shaped or hemispherical, slightly constricted at the throat, and the perianth lobes are triangular-ovate, reflexed outward from the base and lying flat against the perianth tube. The capsule is hemispherical. Flowering occurs in May, and fruiting in June–July.

2. Chinese Asarum: A perennial herb. The rhizome is erect or creeping, with internodes 1–2 cm long. Leaves are usually in pairs; the bud bracts are reniform, with margins sparsely pubescent; the leaf blades are cordate or ovate-cordate, 4–11 cm long and 4.5–13.5 cm wide, with sparse short hairs on the upper surface (more dense along the veins) and hairs only along the veins on the lower surface.Flowers are purplish-black; the perianth tube is campanulate, with sparse, distinct longitudinal ridges on the inner wall; perianth segments are triangular-ovate, erect or nearly spreading. The capsule is nearly spherical. Flowering occurs from April to May, and fruiting from May to June.

3. Seoul Asarum: This variety resembles Hua Asarum, but can be distinguished by the dense short hairs on the underside of the leaf blades and the sparse hairs on the petioles.

Distribution Area

1. Northern Asarum: Distributed in Northeast China, as well as Shanxi, Shandong, Henan, and Shaanxi. 2. Hu Asarum: Distributed in Shaanxi, Shandong, Anhui, Zhejiang, Jiangxi, Henan, Hubei, and Sichuan. 3. Seoul Asarum: Distributed in Liaoning.

Asarum, a name in traditional Chinese medicine, refers to the dried roots and rhizomes of the Araliaceae plant Northern Asarum (Asarum heterotropoides Fr. Schmidt var. mandshurium (Maxim.) Kitag.), Seoul Asarum (Asarum sieboldii Miq. var. seoulense Nakai, or Asarum sieboldii Miq. The first two are commonly known as “Liaoning Asarum” and are mainly produced in Liaoning, Jilin, and Heilongjiang; Asarum sieboldii Miq. is mainly produced in Shaanxi.According to traditional medicine, it has a pungent taste and warm nature, enters the Heart, Lung, and Kidney meridians, and possesses the effects of relieving exterior syndromes and dispelling cold, expelling wind and alleviating pain, unblocking the orifices, and warming the lungs to transform fluid retention. It is primarily used to treat wind-cold colds, headaches, toothaches, nasal congestion with runny nose, nasal discharge, chronic sinusitis, rheumatic arthralgia, and phlegm-fluid retention accompanied by wheezing and cough.