Zixue Dan，Quoted from *Cui’s Formulas* in Volume 31 of *Wai Tai*.，Toxicity from beriberi spreading throughout the body; internal and external fever and restlessness; mouth sores; mania with shouting and running about; sudden jaundice; sudden death from miasma, epidemics, or toxic plagues; warm malaria; the “Five Corpses” and “Five Flows” syndromes; various diseases of the heart and abdomen; loose armpits with stabbing or cutting pain; worm poisoning; heat toxicity from traveling on wild paths; all types of convulsions and epilepsy in children; as well as milk stone and epidemic febrile diseases.For all types of heat toxins in adults and children; stomach heat causing rashes; convulsions, epilepsy, and salivary syncope; “running horse” wasting disease and heat-induced wasting disease; jaundice and emaciation; sore throat; and cases where toxic sores or rashes attack the throat, preventing the passage of food and water.
Zixue Dan
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Formulas Name : Zixue Dan
Chinese Name : 紫雪丹
Drug Formulation
100 liang of gold, 3 jin of cold-water stone, 3 jin of gypsum (one version uses talc), 1 jin of Scrophularia root, 5 liang of ground antelope horn, 5 liang of ground rhinoceros horn, 5 liang of agarwood, 5 liang of blue wood incense, 1 liang of cloves, and 8 liang of licorice (roasted).
Source
Quoted from *Cui’s Formulas* in Volume 31 of *Wai Tai*.
Processing
Chop the ingredients; boil them in 3 dou of water until reduced to 1 dou; strain out the dregs; remove 4 sheng of calcium carbonate (sodium carbonate may also be used); add 10 jin of sodium sulfate to the liquid; simmer over low heat, stirring continuously with a willow strip without stopping; when the mixture begins to set, pour it into a basin; add 3 liang of cinnabar and 1 liang of musk; stir vigorously until it forms a frost-like, snow-white, purplish substance.
Benefits
Toxicity from beriberi spreading throughout the body; internal and external fever and restlessness; mouth sores; mania with shouting and running about; sudden jaundice; sudden death from miasma, epidemics, or toxic plagues; warm malaria; the “Five Corpses” and “Five Flows” syndromes; various diseases of the heart and abdomen; loose armpits with stabbing or cutting pain; worm poisoning; heat toxicity from traveling on wild paths; all types of convulsions and epilepsy in children; as well as milk stone and epidemic febrile diseases.For all types of heat toxins in adults and children; stomach heat causing rashes; convulsions, epilepsy, and salivary syncope; “running horse” wasting disease and heat-induced wasting disease; jaundice and emaciation; sore throat; and cases where toxic sores or rashes attack the throat, preventing the passage of food and water.
Instructions for Use
Mix with water and take 1–2 fen; adjust the dosage as appropriate. One dose is sufficient for 10 years of use.
Copyright: Excerpt from Quoted from *Cui’s Formulas* in Volume 31 of *Wai Tai*., Copyright belongs to the Original Author and all original sources, This article was shared by DeDe on August 31, 2026, Please credit the source and include a link to the original article when reposting.
Terminology Proofreading: [Cheng Bo] | August 31, 2026 Reviewed by: [Wang Zhongxiang, Associate Chief TCM Physician (China)] | August 31, 2026
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Zixue Dan,Toxicity from beriberi spreading throughout the body; internal and external fever and restlessness; mouth sores; mania with shouting and running about; sudden jaundice; sudden death from miasma, epidemics, or toxic plagues; warm malaria; the “Five Corpses” and “Five Flows” syndromes; various diseases of the heart and abdomen; loose armpits with stabbing or cutting pain; worm poisoning; heat toxicity from traveling on wild paths; all types of convulsions and epilepsy in children; as well as milk stone and epidemic febrile diseases.For all types of heat toxins in adults and children; stomach heat causing rashes; convulsions, epilepsy, and salivary syncope; “running horse” wasting disease and heat-induced wasting disease; jaundice and emaciation; sore throat; and cases where toxic sores or rashes attack the throat, preventing the passage of food and water.