Tissue-Regenerating Powder No. 4，*Integrative Dermatology: Chinese and Western Medicine*.，All types of suppurative wounds and ulcers, indurated erythema, ulcers caused by allergic vasculitis, gangrenous pyoderma, and pressure sores, etc.
Tissue-Regenerating Powder No. 4
Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. All references in this article to TCM syndrome differentiation, herbal medicines, teas, and decoctions are intended to promote TCM culture and are provided solely for educational and reference purposes.
Formulas Name : Tissue-Regenerating Powder No. 4
Chinese Name : 生肌散4号
Drug Formulation
Hongshengdan 30g, Frankincense 30g, Myrrh 30g, Borneol 1.5g, Elephant Skin 18g, Calcined Dragon Bone 4.5g, Pearl Shell 15g, Dragon’s Blood 30g, Catechu 30g, Mercury Oxide 9g, Calcined Gypsum 30g, Cuttlefish Bone 4.5g.
Source
*Integrative Dermatology: Chinese and Western Medicine*.
Processing
Grind into a very fine powder.
Benefits
All types of suppurative wounds and ulcers, indurated erythema, ulcers caused by allergic vasculitis, gangrenous pyoderma, and pressure sores, etc.
Instructions for Use
In clinical practice, when there is a large amount of necrotic tissue that is difficult to remove, use Shengji San No. 1 or No. 2, which have strong necrotic-removing and detoxifying effects. When the necrotic tissue has gradually been cleared, switch to Shengji San No. 3; once the necrotic tissue has been almost completely removed, use Shengji San No. 4. If the granulation tissue is healthy and epithelium is growing inward from the edges of the wound, use Shengji San No. 5.Generally, for shallow, flat wounds, when changing dressings, first remove the dressing and clean the area around the wound with dry, non-waxy cotton (do not use alcohol swabs), then use cotton to absorb any secretions.Examine the wound. If there is a significant amount of necrotic tissue inside the wound that is difficult to remove, sprinkle Tissue-Regenerating Powder No. 1 or No. 2 over it (do not use too much; a thin layer covering the wound surface is sufficient), then cover it with gauze coated with Yuhong Ointment and secure it with adhesive tape. The area covered with Yuhong Ointment should not be too large—just slightly larger than the wound itself—and it should not be applied too thickly.Change the dressing every 1–3 days. Once most of the necrotic tissue has been cleared, switch to Tissue-Regenerating Powder No. 3, still covered with Yuhong Ointment. When all necrotic tissue has been completely removed, switch to Tissue-Regenerating Powder No. 4. When granulation tissue has clearly formed, switch to Tissue-Regenerating Powder No. 5 and cover it with Xiangpi Plaster.For deep wounds—particularly those that are small but deep—after removing the dressing, clean the area around the wound with non-woven cotton. Then, use a probe wrapped in a small amount of cotton to wipe away secretions from the depths of the wound (when inserting and removing the probe, maintain a consistent twisting motion in one direction).Finally, place a piece of cotton of appropriate size over the wound, sprinkle Tissue-Regenerating Powder No. 4 onto the cotton, and use the probe to twist and advance it into the wound (ensuring the cotton is wrapped around the probe, with the Tissue-Regenerating Powder No. 4 in the center of the cotton, and that the probe delivers the cotton to the deepest part of the wound).When removing the probe, twist it in the opposite direction; the cotton will have formed a medicated twist and will detach from the probe. Gently withdraw the probe, leaving the cotton twist inside the wound, and securely bandage the exterior with Yuhong Ointment.The application of Shengji Powder is determined by the amount of necrotic tissue in the wound, the size of the wound cavity, and whether drainage is unobstructed. If there is a large amount of necrotic tissue, a small wound cavity, or poor drainage, use No. 1 or No. 2; conversely, use No. 3 or No. 4. If healthy granulation tissue has already formed and the wound has leveled out, No. 5 may be used.
Copyright: Excerpt from *Integrative Dermatology: Chinese and Western Medicine*., Copyright belongs to the Original Author and all original sources, This article was shared by DeDe on August 31, 2026, Please credit the source and include a link to the original article when reposting.
Terminology Proofreading: [Cheng Bo] | August 31, 2026 Reviewed by: [Wang Zhongxiang, Associate Chief TCM Physician (China)] | August 31, 2026
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Tissue-Regenerating Powder No. 4,All types of suppurative wounds and ulcers, indurated erythema, ulcers caused by allergic vasculitis, gangrenous pyoderma, and pressure sores, etc.